Article
Gene loss and compensatory evolution promotes the emergence of morphological novelties in budding yeast.
Nature ecology & evolution - 1 Jun 2022
Farkas Zoltán, Kovács Károly, Sarkadi Zsuzsa, Kalapis Dorottya, Fekete Gergely, Birtyik Fanni, Ayaydin Ferhan, Molnár Csaba, Horváth Péter, Pál Csaba, Papp Balázs
Abstract excerpt
Deleterious mutations are generally considered to be irrelevant for morphological evolution. However, they could be compensated by conditionally beneficial mutations, thereby providing access to new adaptive paths. Here we use high-dimensional phenotyping of laboratory-evolved budding yeast lineages to demonstrate that new cellular morphologies emerge exceptionally rapidly as a by-product of gene loss and...
Topics
- Mutation
- Phenotype
- Saccharomyces cerevisiae
- Saccharomycetales