Article
Utility of molecular subtypes and genetic alterations for evaluating clinical outcomes in 1029 patients with endometrial cancer.
British journal of cancer - 1 Apr 2023
Asami Yuka, Kobayashi Kato Mayumi, Hiranuma Kengo, Matsuda Maiko, Shimada Yoko, Ishikawa Mitsuya, Koyama Takafumi, Komatsu Masaaki, Hamamoto Ryuji, Nagashima Minoru, Terao Yasuhisa, Itakura Atsuo, Kohno Takashi, Sekizawa Akihiko, Matsumoto Koji, Kato Tomoyasu, Shiraishi Kouya, Yoshida Hiroshi
Abstract excerpt
BACKGROUND: We investigated the utility of a molecular classifier tool and genetic alterations for predicting prognosis in Japanese patients with endometrial cancer. METHODS: A total of 1029 patients with endometrial cancer from two independent cohorts were classified into four molecular subtype groups. The primary and secondary endpoints were relapse-free survival (RFS) and overall survival (OS), respectively....
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