Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Establishment of tumor protein p53 mutation-based prognostic signatures for acute myeloid leukemia.

Current research in translational medicine - 1 Sept 2022

Xie Jinye, Chen Kang, Han Hui, Dong Qian, Wang Weijia

Abstract excerpt

PURPOSE: The tumor protein p53 gene (TP53) mutations are associated with poor prognosis of patients with acute myeloid leukemia (AML). This study aimed to establish TP53 mutation-based prognostic risk signatures. PATIENTS AND METHODS: The transcriptomes and clinical characteristics of AML patients were acquired from The Cancer Genome Atlas database, including 11 TP53-mutant samples and 114 TP53-wildtype samples....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Leukemia, Myeloid, Acute

Share to Prognosis

Share to RNA, Long Noncoding

Share to RNA, Messenger

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 35483237
DOI: 10.1016/j.retram.2022.103347

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Establishment of tumor protein p53 mutation-based prognostic signatures for acute myeloid leukemia.PMID 35483237Read ↗

Elucidating the immune landscape and potential prognostic model in acute myeloid leukemia with TP53 mutation.Semantic proximity Read ↗

Identification of key pathways and genes in TP53 mutation acute myeloid leukemia: evidence from bioinformatics analysisSemantic proximity Read ↗

A novel 4‐mRNA signature predicts the overall survival in acute myeloid leukemiaSemantic proximity Read ↗

lncRNA co-expression network model for the prognostic analysis of acute myeloid leukemiaSemantic proximity Read ↗

A novel tp53-associated nomogram to predict the overall survival in patients with pancreatic cancer.Semantic proximity Read ↗

Association Analyses of TP53 Mutation With Prognosis, Tumor Mutational Burden, and Immunological Features in Acute Myeloid Leukemia.Semantic proximity Read ↗

p53 pathway dysfunction is highly prevalent in acute myeloid leukemia independent of TP53 mutational status.Semantic proximity Read ↗

TP53 signal pathway confers potential therapy target in acute myeloid leukemia.Semantic proximity Read ↗

TP53 copy number and protein expression inform mutation status across risk categories in acute myeloid leukemia.Semantic proximity Read ↗

A Novel 85-Gene Expression Signature Predicts Unfavorable Prognosis in Acute Myeloid Leukemia.Semantic proximity Read ↗

Personalized Survival Prediction of Patients With Acute Myeloblastic Leukemia Using Gene Expression ProfilingSemantic proximity Read ↗

[Advances in the Treatment of Acute Myeloid Leukemia with TP53 Mutations-Review].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.