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Article

TP53 signal pathway confers potential therapy target in acute myeloid leukemia.

European journal of haematology - 1 May 2023

Zhu Gelan, Cai Jiayi, Zhong Hua

Abstract excerpt

TP53 mutation is a frequent tumor suppressor mutation and a critical prognostic indicator across studies in many malignant tumors including hematologic malignancies. However, the role of TP53 and its correlative pathway in acute myeloid leukemia (AML) is enigmatic, which may provide possible emerging strategies with the potential to improve outcomes in AML. Accordingly, we focus not only on the TP53 mutation but...

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Identifiers

PMID: 36692074
DOI: 10.1111/ejh.13934

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