Article
Site-wise Diversification of Combinatorial Libraries Using Insights from Structure-guided Stability Calculations.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022
Dolgikh Benedikt, Woldring Daniel
Abstract excerpt
Many auspicious clinical and industrial accomplishments have improved the human condition by means of protein engineering. Despite these achievements, our incomplete understanding of the sequence-structure-function relationship prevents rapid innovation. To tackle this problem, we must develop and integrate new and existing technologies. To date, directed evolution and rational design have dominated as protein...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.