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Transcriptome and Proteome Analysis in LUHMES Cells Overexpressing Alpha-Synuclein

11 Apr 2022

Abstract excerpt

as a model to study pathophysiological processes involved in PD. Previously, we showed that LUHMES cells degenerate after 6 days upon overexpression of wild-type alpha-synuclein. In the present study, we performed a transcriptome and proteome expression analysis in alpha-synuclein-overexpressing cells and GFP-expressing control cells in order to identify genes and proteins that are differentially regulated upon...

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PMID: 35481270
DOI: 10.3389/fneur.2022.787059

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