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Rebiopsy in advanced non-small cell lung cancer, clinical relevance and prognostic implications.

Lung cancer (Amsterdam, Netherlands) - 1 Jun 2022

Scheffler Matthias, Wiesweg Marcel, Michels Sebastian, Nogová Lucia, Kron Anna, Herold Thomas, Scheel Andreas H, Metzenmacher Martin, Eberhardt Wilfried E, Reis Henning, Fassunke Jana, Darwiche Kaid, Aigner Clemens, Schaufler Diana, Riedel Richard, Fischer Rieke, Koleczko Sophia, Schildhaus Hans-Ulrich, Merkelbach-Bruse Sabine, Schmid Kurt W, Büttner Reinhard, Wolf Jürgen, Schuler Martin

Abstract excerpt

INTRODUCTION: Rebiopsies of non-small cell lung cancers (NSCLC) are mainly performed to (i) cover the evolution of potentially amenable resistance mechanisms against a targeted therapy, and (ii) to identify new therapeutic targets which were not detected in the initial diagnostic biopsy. Comprehensive systematic analyses evaluating the value of rebiopsies are missing. METHODS: Clinical databases from two large...

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PMID: 35461051
DOI: 10.1016/j.lungcan.2022.04.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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