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Integrated histological and molecular analyses of rebiopsy samples at osimertinib progression improve post-progression survivals: A single-center retrospective study.

Lung cancer (Amsterdam, Netherlands) - 1 Dec 2020

Cheng Jiang-Tao, Yao Yi-Hui, Gao Yu-Er, Zhang Shi-Ling, Chen Hua-Jun, Wang Zhen, Yan Hong-Hong, Zhou Qing, Tu Hai-Yan, Zhang Xu-Chao, Su Jian, Xie Zhi, Lizaso Analyn, Chen Shu-Yin, Lin Xuan, Xiang Jian-Xing, Wu Yi-Long, Yang Jin-Ji

Abstract excerpt

BACKGROUND: This single-center retrospective cohort study sought to investigate the impact of rebiopsy analysis after osimertinib progression in improving the survival outcomes. METHODS: Eighty-nine patients with EGFR T790M-positive advanced NSCLC who received second- or further-line osimertinib between January 2017 and July 2019 were included in this study. The co-primary study endpoints were post-progression...

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PMID: 33126092
DOI: 10.1016/j.lungcan.2020.10.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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