Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic Mutation Profiling in Head and Neck Paragangliomas.

The Journal of clinical endocrinology and metabolism - 16 Jun 2022

Savvateeva Maria, Kudryavtseva Anna, Lukyanova Elena, Kobelyatskaya Anastasiya, Pavlov Vladislav, Fedorova Maria, Pudova Elena, Guvatova Zulfiya, Kalinin Dmitry, Golovyuk Alexander, Bulavkina Elizaveta, Katunina Irina, Krasnov George, Snezhkina Anastasiya

Abstract excerpt

CONTEXT: Head and neck paragangliomas (HNPGLs) are rare neoplasms with a high degree of heritability. Paragangliomas present as polygenic diseases caused by combined alterations in multiple genes; however, many driver changes remain unknown. OBJECTIVE: The objective of the study was to analyze somatic mutation profiles in HNPGLs. METHODS: Whole-exome sequencing of 42 tumors and matched normal tissues obtained...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Paraganglioma
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Head and Neck Neoplasms

Share to Mutation

Share to Carrier Proteins

Share to RNA-Binding Proteins

Share to Succinate Dehydrogenase

Source

Open in PubMed Open full text

Identifiers

PMID: 35460558
DOI: 10.1210/clinem/dgac250
PMCID: PMC9202733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic Mutation Profiling in Head and Neck Paragangliomas.PMID 35460558Read ↗

Comprehensive Genetic Study of Malignant Cervical Paraganglioma.Semantic proximity Read ↗

Integrative genomic analysis reveals somatic mutations in pheochromocytoma and paraganglioma.Semantic proximity Read ↗

Whole Exome Sequencing Identifies Novel Genetic Alterations in Patients with Pheochromocytoma/Paraganglioma.Semantic proximity Read ↗

Insights into the genetic landscape of pheochromocytomas and paragangliomas in a Brazilian cohort.Semantic proximity Read ↗

Multi-omics analysis defines core genomic alterations in pheochromocytomas and paragangliomas.Semantic proximity Read ↗

Clinical exome next‑generation sequencing panel for hereditary pheochromocytoma and paraganglioma diagnosisSemantic proximity Read ↗

Pheochromocytoma and paraganglioma: molecular testing and personalized medicine.Semantic proximity Read ↗

Germline Mutations and Phenotypic Associations in Korean Patients With Pheochromocytoma and Paraganglioma: A Multicenter Study and Literature Review.Semantic proximity Read ↗

Rare germline mutations identified by targeted next-generation sequencing of susceptibility genes in pheochromocytoma and paraganglioma.Semantic proximity Read ↗

The Changing Paradigm of Head and Neck Paragangliomas: What Every Otolaryngologist Needs to Know.Semantic proximity Read ↗

Targeted next-generation sequencing detects rare genetic events in pheochromocytoma and paragangliomaSemantic proximity Read ↗

Non-Susceptibility Gene Variants in Head and Neck Paragangliomas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.