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Acetylation in the regulation of autophagy

18 Apr 2022

Abstract excerpt

Post-translational modifications, such as phosphorylation, ubiquitination and acetylation, play crucial roles in the regulation of autophagy. Acetylation has emerged as an important regulatory mechanism for autophagy. Acetylation regulates autophagy initiation and autophagosome formation by targeting core components of the ULK1 complex, the BECN1-PIK3C3 complex, and the LC3 lipidation system. Recent studies have...

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PMID: 35435793
DOI: 10.1080/15548627.2022.2062112

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