Article
Clinical impact and proposed application of molecular markers, genetic variants, and cytogenetic analysis in mast cell neoplasms: Status 2022.
The Journal of allergy and clinical immunology - 1 Jun 2022
Arock Michel, Hoermann Gregor, Sotlar Karl, Hermine Olivier, Sperr Wolfgang R, Hartmann Karin, Brockow Knut, Akin Cem, Triggiani Massimo, Broesby-Olsen Sigurd, Reiter Andreas, Gotlib Jason, Horny Hans-Peter, Orfao Alberto, Metcalfe Dean D, Valent Peter
Abstract excerpt
Mast cell neoplasms are an emerging challenge in the fields of internal medicine, allergy, immunology, dermatology, laboratory medicine, and pathology. In this review, we discuss the current standards for the diagnosis and prognostication of mast cell neoplasms with special reference to clinically relevant germline and somatic gene variants. In patients with cutaneous mastocytosis or with indolent systemic...
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