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Article

MutCov: A pipeline for evaluating the effect of mutations in spike protein on infectivity and antigenicity of SARS-CoV-2.

Computers in biology and medicine - 1 Jun 2022

Zhou Wenyang, Xu Chang, Luo Meng, Wang Pingping, Xu Zhaochun, Xue Guangfu, Jin Xiyun, Huang Yan, Li Yiqun, Nie Huan, Jiang Qinghua, Anashkina Anastasia A

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing an outbreak of coronavirus disease 2019 (COVID-19), is a major threat to public health worldwide. Previous studies have shown that the spike protein of SARS-CoV-2 determines viral infectivity and major antigenicity. However, the spike protein has been undergoing various mutations, which bring a great challenge to the prevention and treatment of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35421792
DOI: 10.1016/j.compbiomed.2022.105509
PMCID: PMC8993498

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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