Article
Genetic variation of putative myokine signaling is dominated by biological sex and sex hormones.
eLife - 13 Apr 2022
Velez Leandro M, Van Cassandra, Moore Timothy, Zhou Zhenqi, Johnson Casey, Hevener Andrea L, Seldin Marcus M
Abstract excerpt
Skeletal muscle plays an integral role in coordinating physiological homeostasis, where signaling to other tissues via myokines allows for coordination of complex processes. Here, we aimed to leverage natural genetic correlation structure of gene expression both within and across tissues to understand how muscle interacts with metabolic tissues. Specifically, we performed a survey of genetic correlations focused...
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