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Article

USF1-ATRAP-PBX3 Axis Promote Breast Cancer Glycolysis and Malignant Phenotype by Activating AKT/mTOR Signaling.

International journal of biological sciences - 1 Jan 2022

Wang Dandan, Jin Xiaoying, Lei Mengxia, Jiang Ying, Liu Yali, Yu Fei, Guo Yan, Han Bing, Yang Yue, Sun Weiling, Liu Ying, Zeng Guangchun, Liu Feng, Hu Jing, Chen Xuesong

Abstract excerpt

Angiotensin II type 1 receptor-associated protein (ATRAP) is widely expressed in different tissues and organs, although its mechanistic role in breast cancer remains unclear. Here, we show that ATRAP is highly expressed in breast cancer tissues. Its aberrant upregulation promotes breast cancer aggressiveness and is positively correlated with poor prognosis. Functional assays revealed that ATRAP participates in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35414770
DOI: 10.7150/ijbs.69134
PMCID: PMC8990462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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