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Structural definition of a pan-sarbecovirus neutralizing epitope on the spike S2 subunit

11 Apr 2022

Abstract excerpt

Three betacoronaviruses have crossed the species barrier and established human-to-human transmission causing significant morbidity and mortality in the past 20 years. The most current and widespread of these is SARS-CoV-2. The identification of CoVs with zoonotic potential in animal reservoirs suggests that additional outbreaks could occur. Monoclonal antibodies targeting conserved neutralizing epitopes on...

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PMID: 35411021
DOI: 10.1038/s42003-022-03262-7

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