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Article

A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection

8 Feb 2022

Abstract excerpt

Broadly neutralizing antibodies (bnAbs) to coronaviruses (CoVs) are valuable in their own right as prophylactic and therapeutic reagents to treat diverse CoVs and as templates for rational pan-CoV vaccine design. We recently described a bnAb, CC40.8, from a CoV disease 2019 (COVID-19) convalescent donor that exhibits broad reactivity with human β-CoVs. Here, we showed that CC40.8 targets the conserved S2 stem...

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Identifiers

PMID: 35133175
DOI: 10.1126/scitranslmed.abi9215

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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