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Gut microbiome signatures linked to HIV-1 reservoir size and viremia control

11 Apr 2022

Abstract excerpt

BACKGROUND: The potential role of the gut microbiome as a predictor of immune-mediated HIV-1 control in the absence of antiretroviral therapy (ART) is still unknown. In the BCN02 clinical trial, which combined the MVA.HIVconsv immunogen with the latency-reversing agent romidepsin in early-ART treated HIV-1 infected individuals, 23% (3/13) of participants showed sustained low-levels of plasma viremia during 32...

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PMID: 35410461
DOI: 10.1186/s40168-022-01247-6

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