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Intestinal Microbiota, Microbial Translocation, and Systemic Inflammation in Chronic HIV Infection

23 Jul 2014

Abstract excerpt

BACKGROUND: Despite effective antiretroviral therapy (ART), patients with chronic human immunodeficiency virus (HIV) infection have increased microbial translocation and systemic inflammation. Alterations in the intestinal microbiota may play a role in microbial translocation and inflammation. METHODS: We profiled the fecal microbiota by pyrosequencing the gene encoding 16S ribosomal RNA (rRNA) and measured...

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PMID: 25057045
DOI: 10.1093/infdis/jiu409

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