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Reprogramming the tumor microenvironment by genome editing for precision cancer therapy

11 Apr 2022

Abstract excerpt

The tumor microenvironment (TME) is essential for immune escape by tumor cells. It plays essential roles in tumor development and metastasis. The clinical outcomes of tumors are often closely related to individual differences in the patient TME. Therefore, reprogramming TME cells and their intercellular communication is an attractive and promising strategy for cancer therapy. TME cells consist of immune and...

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PMID: 35410257
DOI: 10.1186/s12943-022-01561-5

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