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Article

Examination of Genetic Susceptibility in Radiation-Associated Meningioma.

Radiation research - 1 Jul 2022

Pemov A, Kim J, Jones K, Vogt A, Sadetzki S, Stewart D R

Abstract excerpt

Previous epidemiological studies have demonstrated elevated susceptibility to ionizing radiation in some families, thus suggesting the presence of genetic components that conferred increased rate of radiation-associated meningioma (RAM). In this study, we exome-sequenced and investigated the segregation pattern of rare deleterious variants in 11 RAM pedigrees. In addition, we performed a rare-variant association...

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Identifiers

PMID: 35405740
DOI: 10.1667/RADE-21-00035.1
PMCID: PMC9326809

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