Article
Genetic predisposition for the development of radiation-associated meningioma: an epidemiological study.
The Lancet. Oncology - 1 May 2007
Flint-Richter Pazit, Sadetzki Siegal
Abstract excerpt
BACKGROUND: Ionising radiation is an established risk factor for meningioma, yet less than 1% of irradiated individuals develop this tumour. Familial aggregation of meningioma is rare. We aimed to assess whether genetic factors can modify the risk for meningioma formation after the initiating effect of radiation, by comparison of the frequency of meningiomas in families that included irradiated and unirradiated...
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