Article
Many hands make light work: CNV of GSTM1 effect on the oral carcinoma risk.
Cancer epidemiology - 1 Jun 2022
Firigato Isabela, López Rossana V M, Curioni Otávio A, De Antonio Juliana, Gattás Gilka Fígaro, de Toledo Gonçalves Fernanda
Abstract excerpt
BACKGROUND: Genetic alterations of oral squamous cell carcinoma (OSCC) allow the understanding of the oral carcinogenesis and the identification of molecular biomarkers that aid the early diagnosis of the disease. The copy number variation (CNV) of GSTM1 and GSTT1 are promising targets because these two genes codify enzymes that perform the inactivation of tobacco carcinogens, which are the main risk factor of...
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