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Article

Association between glucokinase regulator gene polymorphisms and serum uric acid levels in Taiwanese adolescents.

Scientific reports - 1 Apr 2022

Ho Li-Ju, Lu Chieh-Hua, Su Ruei-Yu, Lin Fu-Huang, Su Sheng-Chiang, Kuo Feng-Chih, Chu Nain-Feng, Hung Yi-Jen, Liu Jhih-Syuan, Hsieh Chang-Hsun

Abstract excerpt

The glucokinase regulator gene (GCKR) is located on chromosome 2p23. It plays a crucial role in maintaining plasma glucose homeostasis and metabolic traits. Recently, genome-wide association studies have revealed a positive association between hyperuricemia and GCKR variants in adults. This study investigated this genetic association in Taiwanese adolescents. Data were collected from our previous cross-sectional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35365700
DOI: 10.1038/s41598-022-09393-5
PMCID: PMC8975867

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