Article
Morphologic, immunophenotypic, and molecular genetic comparison study in patients with clonal cytopenia of undetermined significance, myelodysplastic syndrome, and acute myeloid leukemia with myelodysplasia-related changes: A single institution experience.
International journal of laboratory hematology - 1 Aug 2022
Gao Linlin, Hyter Stephen, Zhang Da, Kelting Sarah, Woodroof Janet, Abdallah Al-Ola, Yacoub Abdulraheem, McGuirk Joseph, Abdelhakim Haitham, Godwin Andrew K, Cui Wei
Abstract excerpt
INTRODUCTION: Next-generation sequencing (NGS) analysis showed clonal cytopenia of undetermined significance (CCUS) as an immediate precursor to myelodysplastic syndrome (MDS). METHODS: We evaluated and compared morphologic, multiparametric flow cytometry (MFC), and molecular genetic findings in patients with CCUS (n = 37), MDS (n = 75), and acute myeloid leukemia with myelodysplasia-related changes (AML-MRC,...
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