Article
Clonal cytopenia of undetermined significance (CCUS) with dysplasia is enriched for MDS-type molecular findings compared to CCUS without dysplasia.
European journal of haematology - 1 Apr 2021
Jajosky Audrey N, Sadri Navid, Meyerson Howard J, Oduro Kwadwo A, Kelkar Ashwin, Fitzgerald Brynn, Tomlinson Benjamin, Moore Erika M, Beck Rose C
Abstract excerpt
OBJECTIVES: Although morphologic dysplasia is not typically considered a feature of CCUS, we have consistently observed low-level bone marrow (BM) dysplasia among CCUS patients. We sought to determine whether sub-diagnostic BM dysplasia in CCUS patients is associated with other clinico-pathologic findings of myelodysplastic syndrome (MDS). METHODS: We identified 49 CCUS patients, 25 with sub-diagnostic dysplasia...
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