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Shared Mechanisms for Mutually Exclusive Expression and Antigenic Variation by Protozoan Parasites

8 Mar 2022

Abstract excerpt

Cellular decision-making at the level of gene expression is a key process in the development and evolution of every organism. Variations in gene expression can lead to phenotypic diversity and the development of subpopulations with adaptive advantages. A prime example is the mutually exclusive activation of a single gene from within a multicopy gene family. In mammals, this ranges from the activation of one of...

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PMID: 35350381
DOI: 10.3389/fcell.2022.852239

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