Vascular endothelial growth factor haplotypes are associated with severe ischaemic complications in giant cell arteritis regardless of the disease phenotype.

doi:10.55563/clinexprheumatol/8mku9c

Article

Vascular endothelial growth factor haplotypes are associated with severe ischaemic complications in giant cell arteritis regardless of the disease phenotype.

Clinical and experimental rheumatology - 1 May 2022

Prieto-Peña Diana, Remuzgo-Martínez Sara, Genre Fernanda, Ocejo-Vinyals Javier Gonzalo, Atienza-Mateo Belén, Muñoz-Jimenez Alejandro, Ortiz-Sanjuán Francisco, Romero-Yuste Susana, Moriano Clara, Galíndez-Agirregoikoa Eva, Calvo Itziar, Ortego-Centeno Norberto, Álvarez-Rivas Noelia, Miranda-Filloy Jose A, Llorente Irene, Blanco Ricardo, Gualillo Oreste, Martín Javier, Márquez Ana, Castañeda Santos, Ferraz-Amaro Iván, López-Mejías Raquel, González-Gay Miguel A

Abstract excerpt

OBJECTIVES: To determine whether functional vascular endothelial growth factor (VEGF) polymorphisms influence the expression of the clinical phenotype of giant cell arteritis (GCA). We also evaluated whether VEGF polymorphism is associated with the development of severe ischaemic manifestations in patients with GCA regardless of the clinical phenotype, classic cranial GCA or predominantly extracranial GCA large...

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Vascular endothelial growth factor haplotypes are associated with severe ischaemic complications in giant cell arteritis regardless of the disease phenotype.

Abstract excerpt

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