Article
A functional variant of vascular endothelial growth factor is associated with severe ischemic complications in giant cell arteritis.
The Journal of rheumatology - 1 Sept 2005
Rueda Blanca, Lopez-Nevot Miguel A, Lopez-Diaz Maria J, Garcia-Porrua Carlos, Martín Javier, Gonzalez-Gay Miguel A
Abstract excerpt
OBJECTIVE: Angiogenesis, the formation of new blood vessels, may play a role in giant cell arteritis (GCA), the most common type of systemic vasculitis in the elderly in Western countries. Vascular endothelial growth factor (VEGF) is one of the most important proangiogenic mediators. We wanted to assess the potential role of -1154 G-->A (rs1570360) and -634 G-->C (rs2010963) VEGF gene functional variants in GCA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
