Article
Endothelial nitric oxide synthase gene polymorphisms in giant cell arteritis.
Arthritis and rheumatism - 1 Nov 2003
Salvarani Carlo, Casali Bruno, Nicoli Davide, Farnetti Enrico, Macchioni Pierluigi, Catanoso Maria Grazia, Chen Qingquan, Bajocchi GianLuigi, Boiardi Luigi
Abstract excerpt
OBJECTIVE: To examine potential associations of the Glu/Asp(298) polymorphism in exon 7 and the 4a/b polymorphism in intron 4 of the endothelial nitric oxide synthase (eNOS) gene with susceptibility to and clinical expression of giant cell arteritis (GCA), particularly in patients with versus those without ischemic complications. METHODS: Ninety-one consecutive patients with biopsy-proven GCA, who were residents...
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