Article
High Frequency of ASXL1 and IDH Mutations in Young Acute Myeloid Leukemia Egyptian Patients.
Asian Pacific journal of cancer prevention : APJCP - 1 Mar 2022
El Nahass Yasser H, Nader Heba A, Sabet Salwa, Nooh Hend A, Bassiony Heba, Kamel Mahmoud, Samra Mohamed A, Mahmoud Hossam K, El Metnawy Wafaa H, El Refaey Fatma A
Abstract excerpt
BACKGROUND: Prognostication of AML patients depends on association of genetic and epigenetic abnormalities. We aimed to evaluate the frequency and prognostic significance of Additional Sex comb's Like1 (ASXL1), Isocitrate Dehydrogenase (IDH) and Casitas B- lineage Lymphoma (CBL) mutations in AML assessing their association with different cytogenetic risk category. METHODS: We used High Resolution Melting (HRM)...
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