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Article

Oxidative stress facilitates exogenous mitochondria internalization and survival in retinal ganglion precursor-like cells

24 Mar 2022

Abstract excerpt

Ocular cells are highly dependent on mitochondrial function due to their high demand of energy supply and their constant exposure to oxidative stress. Indeed, mitochondrial dysfunction is highly implicated in various acute, chronic, and genetic disorders of the visual system. It has recently been shown that mitochondrial transplantation (MitoPlant) temporarily protects retinal ganglion cells (RGCs) from cell...

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PMID: 35332189
DOI: 10.1038/s41598-022-08747-3

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