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Article

Regulators of Androgen Action Resource: a one-stop shop for the comprehensive study of androgen receptor action

14 Feb 2016

Abstract excerpt

Androgen receptor (AR) is a ligand-activated transcription factor that is the main target for treatment of non-organ-confined prostate cancer (CaP). Failure of life-prolonging AR-targeting androgen deprivation therapy is due to flexibility in steroidogenic pathways that control intracrine androgen levels and variability in the AR transcriptional output. Androgen biosynthesis enzymes, androgen transporters and...

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PMID: 26876983
DOI: 10.1093/database/bav125

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