Article
Reverse Electrochemical Sensing of FLT3-ITD Mutations in Acute Myeloid Leukemia Using Gold Sputtered ZnO-Nanorod Configured DNA Biosensors.
Biosensors - 10 Mar 2022
Thevendran Ramesh, Foo Kai Loong, Hussin Mohd Hazwan, Moses Emmanuel Jairaj, Citartan Marimuthu, Prasad Haarindraprasad Rajintra, Maheswaran Solayappan
Abstract excerpt
Detection of genetic mutations leading to hematological malignancies is a key factor in the early diagnosis of acute myeloid leukemia (AML). FLT3-ITD mutations are an alarming gene defect found commonly in AML patients associated with high cases of leukemia and low survival rates. Available diagnostic assessments for FLT3-ITD are incapable of combining cost-effective detection platforms with high analytical...
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