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Article

Preoperative detection of KRAS mutated circulating tumor DNA is an independent risk factor for recurrence in colorectal cancer.

Scientific reports - 11 Jan 2021

Nakamura Yuki, Yokoyama Shozo, Matsuda Kenji, Tamura Koichi, Mitani Yasuyuki, Iwamoto Hiromitsu, Mizumoto Yuki, Murakami Daisuke, Kitahata Yuji, Yamaue Hiroki

Abstract excerpt

Preoperative ctDNA status in relation to recurrence in cases of CRC remains unclear. We examined preoperative ctDNA detection by targeting KRAS gene mutations as a predictive marker for recurrence after CRC surgery. We measured the preoperative KRAS mutated ctDNA status and analyzed the correlation with clinicopathologic features of 180 patients that underwent surgery for CRC. We studied the association between...

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Identifiers

PMID: 33432066
DOI: 10.1038/s41598-020-79909-4
PMCID: PMC7801374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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