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Article

TARSII and CARSII: Two approaches for SNP-independent identification of germline differentially methylated regions in mammals.

STAR protocols - 17 Jun 2022

Zhang Wenhao, Zhang Yi

Abstract excerpt

Identifying germline differentially methylated regions (DMRs) in outbred mammals remains a challenge because of difficulty in obtaining single-nucleotide polymorphisms (SNPs). To overcome this difficulty, we developed two computational approaches, TARSII and CARSII, which allow accurate prediction of germline DMRs from DNA methylomes independent of SNPs. Furthermore, we introduce an easy and quick way to validate...

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Identifiers

PMID: 35310079
DOI: 10.1016/j.xpro.2022.101240
PMCID: PMC8931438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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