Article
Performance of methods to detect genetic variants from bisulphite sequencing data in a non-model species.
Molecular ecology resources - 1 Feb 2022
Lindner Melanie, Gawehns Fleur, Te Molder Sebastiaan, Visser Marcel E, van Oers Kees, Laine Veronika N
Abstract excerpt
The profiling of epigenetic marks like DNA methylation has become a central aspect of studies in evolution and ecology. Bisulphite sequencing is commonly used for assessing genome-wide DNA methylation at single nucleotide resolution but these data can also provide information on genetic variants like single nucleotide polymorphisms (SNPs). However, bisulphite conversion causes unmethylated cytosines to appear as...
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