Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identifying metabolic reprogramming phenotypes with glycolysis-lipid metabolism discoordination and intercellular communication for lung adenocarcinoma metastasis.

Communications biology - 17 Mar 2022

Li Xin, Tang Lefan, Deng Jiaxing, Qi Xiuying, Zhang Juxuan, Qi Haitao, Li Mengyue, Liu Yixin, Zhao Wenyuan, Gu Yunyan, Qi Lishuang, Li Xia

Abstract excerpt

Tumor metastasis imposes metabolic requirements for escaping from primary tissues, producing vulnerability in treatment. This study aimed to explore the metabolic reprogramming relevant to lung adenocarcinoma (LUAD) metastasis and decode the underlying intercellular alterations. Using the gene expression profiles of 394 LUAD samples derived from The Cancer Genome Atlas (TCGA), we identified 11 metastasis-related...

Topics

Join the communities discussing this publication.

Adenocarcinoma of Lung
Cell Communication
Endothelial Cells
Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kelch-Like ECH-Associated Protein 1

Lipid Metabolism

NF-E2-Related Factor 2

Source

Open in PubMed Open full text

Identifiers

PMID: 35301413
DOI: 10.1038/s42003-022-03135-z
PMCID: PMC8931047

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identifying metabolic reprogramming phenotypes with glycolysis-lipid metabolism discoordination and intercellular communication for lung adenocarcinoma metastasis.PMID 35301413Read ↗

Development and validation of a metabolic gene signature for predicting the overall survival of patients in lung adenocarcinoma with lymph node metastasisSemantic proximity Read ↗

Comprehensive analyses of metabolism-related lncRNA for LUADSemantic proximity Read ↗

Identified lung adenocarcinoma metabolic phenotypes and their association with tumor immune microenvironment.Semantic proximity Read ↗

Identification of a 5-Gene Metabolic Signature for Predicting Prognosis Based on an Integrated Analysis of Tumor Microenvironment in Lung AdenocarcinomaSemantic proximity Read ↗

Novel Lipid Metabolism-Related Gene Signature in Lung Adenocarcinoma Patients Experiencing Lymph Node MetastasisSemantic proximity Read ↗

Shining a light on metabolic vulnerabilities in non-small cell lung cancer.Semantic proximity Read ↗

Metabolic alterations and immune heterogeneity in gastric cancer metastasisSemantic proximity Read ↗

Pan-cancer characterization of metabolism-related biomarkers identifies potential therapeutic targetsSemantic proximity Read ↗

Novel Lipid Metabolism-Related Gene Signature Associated with Clinical and Immune Features in Lung Adenocarcinoma Patients Experiencing Lymph Node MetastasisSemantic proximity Read ↗

The dynamic dysregulated network identifies stage-specific markers during lung adenocarcinoma malignant progression and metastasisSemantic proximity Read ↗

Alternative Energy: Breaking Down the Diverse Metabolic Features of Lung CancersSemantic proximity Read ↗

Therapeutic strategies of metabolic reprogramming in non-small cell lung carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.