Article
Shining a light on metabolic vulnerabilities in non-small cell lung cancer.
Biochimica et biophysica acta. Reviews on cancer - 1 Jan 2021
Dowling Catríona M, Zhang Hua, Chonghaile Tríona Ní, Wong Kwok-Kin
Abstract excerpt
Metabolic reprogramming is a hallmark of cancer which contributes to essential processes required for cell survival, growth, and proliferation. Non-small cell lung cancer (NSCLC) is the most common type of lung cancer and its genomic classification has given rise to the design of therapies targeting tumors harboring specific gene alterations that cause aberrant signaling. Lung tumors are characterized with having...
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