Article
Gattaca: Base-Pair Resolution Mutation Tracking for Somatic Evolution Studies using Agent-based Models.
Molecular biology and evolution - 11 Apr 2022
Schenck Ryan O, Brosula Gabriel, West Jeffrey, Leedham Simon, Shibata Darryl, Anderson Alexander R A
Abstract excerpt
Research over the past two decades has made substantial inroads into our understanding of somatic mutations. Recently, these studies have focused on understanding their presence in homeostatic tissue. In parallel, agent-based mechanistic models have emerged as an important tool for understanding somatic mutation in tissue; yet no common methodology currently exists to provide base-pair resolution data for these...
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