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Present state and future perspectives of using pluripotent stem cells in toxicology research

11 Jan 2011

Abstract excerpt

The use of novel drugs and chemicals requires reliable data on their potential toxic effects on humans. Current test systems are mainly based on animals or in vitro-cultured animal-derived cells and do not or not sufficiently mirror the situation in humans. Therefore, in vitro models based on human pluripotent stem cells (hPSCs) have become an attractive alternative. The article summarizes the characteristics of...

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PMID: 21225242
DOI: 10.1007/s00204-010-0641-6

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