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Article

Complexities of Next-Generation Sequencing in Solid Tumors: Case Studies.

Journal of the National Comprehensive Cancer Network : JNCCN - 1 Sept 2020

Sokolova Alexandra O, Shirts Brian H, Konnick Eric Q, Tsai Ginger J, Goulart Bernardo H L, Montgomery Bruce, Pritchard Colin C, Yu Evan Y, Cheng Heather H

Abstract excerpt

With the promise and potential of clinical next-generation sequencing for tumor and germline testing to impact treatment and outcomes of patients with cancer, there are also risks of oversimplification, misinterpretation, and missed opportunities. These issues risk limiting clinical benefit and, at worst, perpetuating false conclusions that could lead to inappropriate treatment selection, avoidable toxicity, and...

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Identifiers

PMID: 32886903
DOI: 10.6004/jnccn.2020.7569

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