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Regulation of Ferroptosis by Amino Acid Metabolism in Cancer

1 Jan 2022

Abstract excerpt

Ferroptosis, a new form of programmed necrosis characterized by iron-dependent lethal accumulation of lipid hydroperoxides, is associated with many human diseases. Targeting amino acid (AA) availability can selectively suppress tumor growth and has been a promising therapeutic strategy for cancer therapy. Compelling studies have indicated that AA metabolism is also involved in ferroptosis, closely regulating its...

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Share to Ferroptosis and cancer prognosis
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Identifiers

PMID: 35280684
DOI: 10.7150/ijbs.64982

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