Article
Regulation of Ferroptosis by Amino Acid Metabolism in Cancer
1 Jan 2022
Abstract excerpt
Ferroptosis, a new form of programmed necrosis characterized by iron-dependent lethal accumulation of lipid hydroperoxides, is associated with many human diseases. Targeting amino acid (AA) availability can selectively suppress tumor growth and has been a promising therapeutic strategy for cancer therapy. Compelling studies have indicated that AA metabolism is also involved in ferroptosis, closely regulating its...
Topics
Join the communities discussing this publication.