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Article

Pleiotropic cancer manifestations of germline CDH1 mutations: Risks and management.

Journal of surgical oncology - 1 Jun 2022

Corso Giovanni

Abstract excerpt

Germline CDH1 defects are related with the development of multiple cancers due its pleiotropic nature. These several conditions are associated with various risks of penetrance and with different clinical management strategies. In this clinical review, we described the penetrance risks of gastric, breast, prostate, and colorectal cancers, in CDH1 carriers, within as well as outside the familial setting, and the...

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Share to Antigens, CD
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Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35277969
DOI: 10.1002/jso.26847
PMCID: PMC9313879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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