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Functional genomics of RAP proteins and their role in mitoribosome regulation in Plasmodium falciparum

11 Mar 2022

Abstract excerpt

The RAP (RNA-binding domain abundant in Apicomplexans) protein family has been identified in various organisms. Despite expansion of this protein family in apicomplexan parasites, their main biological functions remain unknown. In this study, we use inducible knockdown studies in the human malaria parasite, Plasmodium falciparum, to show that two RAP proteins, PF3D7_0105200 (PfRAP01) and PF3D7_1470600 (PfRAP21),...

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PMID: 35277503
DOI: 10.1038/s41467-022-28981-7

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