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Article

Targeting Myotonic Dystrophy Type 1 with Metformin.

International journal of molecular sciences - 7 Mar 2022

García-Puga Mikel, Saenz-Antoñanzas Ander, Matheu Ander, López de Munain Adolfo

Abstract excerpt

Myotonic dystrophy type 1 (DM1) is a multisystemic disorder of genetic origin. Progressive muscular weakness, atrophy and myotonia are its most prominent neuromuscular features, while additional clinical manifestations in multiple organs are also common. Overall, DM1 features resemble accelerated aging. There is currently no cure or specific treatment for myotonic dystrophy patients. However, in recent years a...

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Identifiers

PMID: 35270043
DOI: 10.3390/ijms23052901
PMCID: PMC8910924

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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