Article
Monocyte secretory profiling in a clinical and MEFV genotype-characterized cohort of Danish familial Mediterranean fever patients: diagnostic potential of CCL1 and CXCL1.
Scandinavian journal of rheumatology - 1 Mar 2023
Mortensen S B, Hansen A E, Byg K-E, Diederichsen L, Schade Larsen C, Goldschmidt M I, Jakobsen M A, Assing K, Lambertsen K L, Andersen D C, Johansen I S
Abstract excerpt
OBJECTIVE: The autoinflammatory disease familial Mediterranean fever (FMF), characterized by recurrent attacks of sterile fever, serosal, and/or synovial inflammation, is caused by variants in the Mediterranean fever gene, MEFV, coding for the pyrin inflammasome sensor. The diagnosis of FMF is mainly based on clinical symptoms and confirmed by detection of disease-associated MEFV variants. However, the diagnosis...
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