Article
Common Variable Immunodeficiency-Associated Cancers: The Role of Clinical Phenotypes, Immunological and Genetic Factors.
Frontiers in immunology - 1 Jan 2022
Bruns Luzia, Panagiota Victoria, von Hardenberg Sandra, Schmidt Gunnar, Adriawan Ignatius Ryan, Sogka Eleni, Hirsch Stefanie, Ahrenstorf Gerrit, Witte Torsten, Schmidt Reinhold Ernst, Atschekzei Faranaz, Sogkas Georgios
Abstract excerpt
OBJECTIVE: The aim of this study was to investigate the prevalence of cancer and associating clinical, immunological, and genetic factors in a German cohort of patients with common variable immunodeficiency (CVID). METHODS: In this retrospective monocenter cohort study, we estimated the standardized incidence ratio (SIR) for different forms of cancer diagnosed in CVID patients. Furthermore, we evaluated the...
Topics
- Arthritis
- Cohort Studies
- Common Variable Immunodeficiency
- Genetic Predisposition to Disease
- Humans
- Lung Diseases, Interstitial
- Lymphoma, Non-Hodgkin
- Phenotype
- Retrospective Studies
- Stomach Neoplasms