Article
Epidemiology and pathophysiology of malignancy in common variable immunodeficiency?
Allergologia et immunopathologia - 1 Jan 2000
Tak Manesh A, Azizi G, Heydari A, Kiaee F, Shaghaghi M, Hossein-Khannazer N, Yazdani R, Abolhassani H, Aghamohammadi A
Abstract excerpt
Common variable immunodeficiency (CVID) is a diagnostic category of primary immunodeficiency (PID) which may present with heterogeneous disorders including recurrent infections, autoimmunity, granulomatous diseases, lymphoid and other types of malignancies. Generally, the incidence of malignancy in CVID patients is around 1.5-20.7% and usually occurs during the 4th-6th decade of life. Non-Hodgkin lymphoma is the...
Topics
- Age Factors
- Common Variable Immunodeficiency
- Gene-Environment Interaction
- Genetic Predisposition to Disease
- Homeostasis
- Humans
- Immune System
- Incidence
- Neoplasms