Article
[Genetic basis of common variable immunodeficiency: from common to variable].
Annales de biologie clinique - 1 Oct 2021
Allaoui Abire, Mokhantar Khaoula, Jeddane Leila, Dehbi Hind, Ailal Fatima, Bousfiha Ahmed Aziz, Elkabli Hassan, Moudatir Mina
Abstract excerpt
Common variable immunodeficiency (CVID) is one of the most prevalent primary immunodeficiencies. It is characterized by hypogammaglobulinaemia, increased susceptibility to infections and impaired vaccine responses. CVID has an important, clinical, immunological and genetic heterogeneity. A minority of patients present with monogenic forms in CVID, unlike other primary immunodeficiencies. With the development of...
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