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Article

SARS-CoV-2's high rate of genetic mutation under immune selective pressure: from oropharyngeal B.1.1.7 to intrapulmonary B.1.533 in a vaccinated patient.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 May 2022

Musso Nicolò, Maugeri Jessica Giuseppina, Bongiorno Dafne, Stracquadanio Stefano, Bartoloni Giovanni, Stefani Stefania, Di Stefano Emanuela Daniela

Abstract excerpt

This is the case report of an 84-year-old man affected by COVID-19 between the 2 doses of vaccination, with negative exitus. We analyzed nasopharyngeal samples of viral RNA collected during the disease and nasopharyngeal and lung samples collected postmortem by reverse transcription LAMP (RT-LAMP) PCR and Next Generation Sequencing (NGS). NGS results were analyzed with different bioinformatic tools to define...

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Identifiers

PMID: 35247550
DOI: 10.1016/j.ijid.2022.02.044
PMCID: PMC8888350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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